Bio-Medical Informatics Group

Research Areas

Medical Image Processing  

Development of algorithms for the enhancement, interpolation, segmentation of medical images from various medical imaging (X-ray, CT, MRI, PET, SPECT, ultrasound). Development of algorithms based on Mathematical Morphology, fractal theory, wavelets, texture analysis, and object-oriented techniques for the digital processing of 1D, 2D and 3D medical data.

Automatic Registration and Fusion of Multidimensional Medical Data

Techniques for the automatic registration and fusion of various medical data from different imaging modalities (CT, MRI, PET, SPECT, portal images, fundus camera). Development of various algorithms for the semi-automatic registration of portal images, the automatic surface-based registration, the automatic volume-based registration and the automatic elastic-based registration. Development of fusion techniques based on mathematical morphology, logical operations, pseudo-coloring and classification techniques. Development of integrated systems for the registration and fusion of various medical data and installation on real clinical environment.

Optimization Techniques and Application to Bioinformatics

Algorithms for the optimal solution of problems in the field of bioinformatics such as registration of medical data, classification of biosignals, etc using various optimization techniques. Development and implementation of local and global optimization techniques such as Downhill Simplex, Powell Method, Simulated Annealing, and Genetics Algorithms.

Digital Biosignal Processing

Algorithms of processing various biosignals in order to identify features that describe the signals. Processing of EEG (Evoked Potentials) and ECG, using multivariate autoregressive models and fractal theory.

Visualization of Medical Data

Algorithms and tools for the visualization of multidimensional medical data from different medical image modalities. Development o various algorithms for the 3D and 4D visualization of medical data based on a modification of the Marching Cubes algorithm, the Self Organizing Maps and Growing Cells Structure.

Development of Decision Support Systems

Medical image processing techniques in conjunction with neural networks for the classification of biosignals and images and the support of the diagnosis in a clinical environment. Decision support systems based on neural networks, fuzzy logic and genetics algorithms.

Medical Information Systems

Electronic patient record. Data archiving in DICOM 3.0 format and medical data transmission using compression algorithms. Telematics application with various hospital sides. Management Information System for the reengineering of the biomedical-equipment procurement process. Web-based system for the archiving and processing of gynecological data.

Telemedicine Applications

Developed an integrated system for the acquisition and transmission of medical data between distant medical units. Recently, such a system has been installed in a Healthcare Unit in the island of Samothraki (Greece), allowing the transmission of 1D (e.g. ECG, EEG) and 2D (x-ray images) medical data to the Hospital ofAlexandroupoli (Greece). Furthermore, a pilot application for the transmission of medical data, using the WEB is being under development between the Aretaieio Hospital(Athens), the Aiginiteio Hospital (Athens) and the Metropolitan Hospital of Offenbach (Germany).